Kikuchi-Fujimoto病,或称组织细胞坏死性淋巴结炎,是一种自限性疾病。其特征是良性的淋巴结肿大,可伴有发热和系统性症状。该病最常累及亚裔人,常为小于40岁的年轻成人患者。受累淋巴结常显示副皮质区凋亡坏死,可见大量核碎片以及组织细胞、浆样树突细胞和CD8阳性的T细胞增生,? Kikuchi-Fujimoto disease, or tissue necrosis lymphadenitis, is a self-limiting disease. It is characterized by benign lymphadenopathy, which may be accompanied by fever and systemic symptoms. The disease most commonly affects Asians, often young adults younger than 40 years. Involved lymph nodes often show apoptosis and necrosis of the paracortex, showing a large number of nuclear debris and tissue cells, plasma-like dendritic cells and CD8-positive T cell proliferation?