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目的 分析听神经瘤的大小、生长速率及增殖与其磁共振信号、组织学特征之间的相互关系。方法 回顾分析听神经瘤 4 3例 ,依MR信号分为均匀、不均匀及囊性变 ,组织学包括AntoniA、AntoniB以及纤维化、含铁血黄素沉淀、黄色瘤样细胞。结果 信号均匀的听神经瘤肿瘤较小、生长较慢、增殖指数较低 ,组织学以AntoniA结构占优 ;不均匀和囊性听神经瘤肿瘤较大、生长较快、增殖指数较高 ,以混合型结构占优 ;不均匀和囊性听神经瘤中含铁血黄素沉淀、黄色瘤样细胞以及不均匀听神经瘤的纤维化明显增多 ,它们均有统计学意义。结论 较大的听神经瘤不仅MR表现为不均匀信号 ,而且组织学主要表现混合型结构 ,也可能有其他变化 ,主要是含铁血黄素沉淀和囊性变。
Objective To analyze the relationship between the size, growth rate and proliferation of acoustic neuroma and its magnetic resonance signals and histological features. Methods A retrospective analysis of 43 cases of acoustic neuroma, according to the MR signal is divided into uniform, uneven and cystic degeneration, histology, including AntoniA, AntoniB and fibrosis, hemosiderin pellet, xanthinoid cells. Results The signal homogeneous acoustic neuroma tumor was smaller, grew slowly, the proliferation index was lower, and histology dominated the structure of AntoniA. The heterogeneity and cystic acoustic neuroma tumors were larger, grew faster, and had a higher proliferation index. The mixed type Structure dominant; uneven and cystic acoustic neuroma hemosiderin precipitation, yellow tumor-like cells and heterogeneous acoustic neuroma fibrosis significantly increased, and they were statistically significant. CONCLUSIONS: Larger acoustic neuromas not only show non-uniform MR signals, but also histological manifestations of mixed structures and may have other changes, mainly hemosiderin deposition and cystic degeneration.