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目的探讨FGR与孕妇血清中甲状腺素的关系。方法采用放射免疫分析法,测定正常足月妊娠38例(正常组)和足月妊娠FGR 22例(FGR组)孕妇血清中甲状腺素(T4)、三碘甲状腺原氨酸(T3)、游离T4(FT4)、游离T3(FT3)、促甲状腺素(TSH)水平,比较两组甲状腺素水平。结果 FGR组孕妇血清TSH高于对照组(P<0.01),T4、T3、FT4、FT3均低于对照组,其中T4、FT4差异有显著性意义(P<0.05)。结论 FGR的发病可能与甲状腺功能低下有关。
Objective To investigate the relationship between FGR and serum thyroxine in pregnant women. Methods Serum levels of thyroxine (T4), triiodothyronine (T3), free T4 in normal pregnant women and normal pregnant women in FGR group (FGR group) were measured by radioimmunoassay. (FT4), free T3 (FT3) and thyroid-stimulating hormone (TSH) were measured. The levels of thyroxine in both groups were compared. Results The levels of serum TSH in FGR group were significantly higher than those in control group (P <0.01). The levels of T4, T3, FT4 and FT3 in FGR group were lower than those in control group (P <0.05). Conclusion The incidence of FGR may be related to hypothyroidism.