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目的考察抗菌药物专项整治活动对我院妇产科剖宫产围术期预防性应用抗菌药物的影响。方法采用回顾性调查的方法调取2011年、2013年、2015年第一季度所有的妇产科剖宫产手术病例,对其抗菌药物的使用情况进行汇总分析。结果抗菌药物选择的合理率由2011年的33.3%,明显提升到2013年的90.0%(P<0.05),并在2015年进一步提升到96.1%(P>0.05);预防用药时机的合理率由2011年的7.7%明显提升到2013年的52.5%(P<0.05),到2015年进一步提升到93.5%(P<0.05);用药疗程在术后24h内停药率由2011年的6.4%明显提升到2013年的68.8%(P<0.05),到2015年进一步提升到97.4%(P<0.05)。结论抗菌药物专项整治活动明显提升了我院妇产科剖宫产围术期的抗菌药物应用合理性,且能持续改进,并没有出现反弹现象。
Objective To investigate the special antimicrobial treatment activities in our hospital obstetrics and gynecology cesarean section perioperative prophylactic antimicrobial drugs. Methods A retrospective survey of all cases of obstetrics and gynecology cesarean section in 2011, 2013 and the first quarter of 2015 was conducted to analyze the use of antibacterials. Results The reasonable rate of antimicrobial drug selection increased significantly from 33.3% in 2011 to 90.0% in 2013 (P <0.05), and further increased to 96.1% in 2015 (P> 0.05). The reasonable rate of preventive medication was 7.7% in 2011 increased significantly to 52.5% (P <0.05) in 2013 and further increased to 93.5% in 2015 (P <0.05). The discontinuation rate of drug treatment within 24 hours after operation was significantly increased from 6.4% in 2011 Increased to 68.8% in 2013 (P <0.05) and further increased to 97.4% in 2015 (P <0.05). Conclusion The special rectification activities of antimicrobial drugs significantly improved the rationality of antibacterials application during the perioperative period of cesarean section in our hospital, and can continue to improve, and there is no rebound phenomenon.