自从1963年Reye等记述脑病和脂肪肝综合症(Reye氏综合症)以来,报告的病例已有所增加。这种综合症的死亡率较高,其病原因子还未肯定,毒素或病毒感染似认为是主要的。本文对24例诊断为Reye氏综合症的病人进行了研究,以探讨该综合症是否与接触毒素或病毒感染有关。 1974年1～3月间发现的24例Reye氏综合症中,16例得到肝活检的确诊。患者年龄从5(1/2)月～14(1/2)岁(平均7.7岁),男性14例,女性10例。21例有呼吸道症状,其前驱 Since Reye et al. (1963) described encephalopathy and fatty liver syndrome (Reye’s syndrome), the reported cases have increased. The high mortality rate of this syndrome, the etiological factor is not yet confirmed, toxin or virus infection seems to be considered the main. In this paper, 24 patients diagnosed with Reye’s syndrome were studied to investigate whether the syndrome is associated with exposure to toxins or viral infections. Of the 24 Reye’s syndromes found between January and March 1974, 16 were confirmed by liver biopsy. Patients ranged in age from 5 (1/2) months to 14 (1/2) years (mean, 7.7 years), with 14 males and 10 females. 21 cases of respiratory symptoms, its precursor