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对于Ｇｒａｖｅｓ病患者接受一次或二次碘治疗后发生甲低的７０例进行了分析。将甲低分为近期、远期、一过性和永久性甲低，分析了各种甲低发生的情况并比较了甲状腺大小、性别、年龄、病程、是否用过抗甲状腺药物以及~（１３１）Ｉ剂量大小等因素与甲低发生的关系。通过分析发现甲状腺越小，甲低的发生率越高且容易成为永久性甲低；近期永久性甲低的发生率女性明显高于男性；甲低发生的本质是个体对~（１３１）Ｉ的辐射敏感性较高，但~（１３１）Ｉ剂量越大，可以使超过耐受限度的患者越多，因而甲低的发生率也就越高；甲低的发生与病程和年龄的关系不大；未用过抗甲状腺药物治疗者，一过性甲低的发生率明显增高，但永久性甲低的发生无明显差别。对于接受第二次~（１３１）Ｉ治疗的患者，甲低发生有增多的趋势。
Seventy patients with hypothyroidism who underwent primary or secondary iodine treatment of Graves’ disease were analyzed. A hypothyroidism is divided into short-term, long-term, transient and permanent hypothyroidism, analyzed a variety of hypothyroidism occurred and compared thyroid size, gender, age, duration, whether anti-thyroid drugs used and 131 ) I dose size and other factors and hypothyroidism. Through the analysis found that the smaller the thyroid, the lower the incidence of hypothyroidism and easy to become permanent hypothyroidism; the recent incidence of permanent hypothyroidism was significantly higher in women than men; hypothyroidism is the essence of the individual to 131I Higher radiation sensitivity, but the dose of ~ (131) I, the more patients can exceed the tolerance limit, and therefore the lower the incidence of hypothyroidism; hypothyroidism and disease duration and age is not ; No anti-thyroid drug treatment, transient hypothyroidism was significantly increased, but the incidence of permanent hypothyroidism no significant difference. For patients receiving second ~ (131) I treatment, there is an increasing trend of hypothyroidism.