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目的:观察联合鼻饲生大黄粉对严重脓毒症的白细胞(WBC)、降钙素原(PCT)、C-反应蛋白(CRP)及血清乳酸(LAC)的变化。方法:将50例诊断为严重脓毒症患者随机分为对照组和观察组,各25例,对照组单予西医治疗,观察组在对照组的基础上联合鼻饲生大黄细粉治疗。结果:观察组外周血WBC、PCT、CRP及LAC明显低于对照组,差异具有统计学意义(P<0.05)。结论:与单纯西医治疗相比,联合鼻饲生大黄细粉能明显改善严重脓毒症患者的外周血WBC、PCT、CRP及LAC水平,减轻炎症病理反应,有助于改善其预后。
Objective: To observe the changes of white blood cells (WBC), procalcitonin (PCT), C-reactive protein (CRP) and serum lactate (LAC) Methods: Fifty patients diagnosed as severe sepsis were randomly divided into control group and observation group, with 25 cases in each group. The control group was treated with Western medicine alone. The observation group was treated with nasal feeding rhubarb powder on the basis of the control group. Results: The WBC, PCT, CRP and LAC in the peripheral blood of the observation group were significantly lower than those of the control group (P <0.05). Conclusion: Compared with western medicine alone, nasal feeding rhubarb powder can significantly improve WBC, PCT, CRP and LAC in peripheral blood of patients with severe sepsis, relieve inflammatory pathological changes and improve prognosis.