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目的观察泮托拉唑在治疗上消化道出血中的临床疗效。方法 80例上消化道出血患者,随机分为观察组与对照组,每组40例。分别给予观察组及对照组患者泮托拉唑、奥美拉唑治疗,治疗5 d后观察两组临床疗效。结果观察组患者治疗有效率为95%,不良反应发生率7.5%,明显优于对照组的70%和15.0%,两组对比差异有统计学意义(P<0.05)。观察组患者止血时间为(1.5±0.5)d,明显短于对照组的(3.0±0.5)d,两组对比差异有统计学意义(P<0.05)。结论泮托拉唑在治疗上消化道出血中止血显著,不良反应少,临床应用价值显著。
Objective To observe the clinical efficacy of pantoprazole in the treatment of upper gastrointestinal bleeding. Methods 80 cases of upper gastrointestinal bleeding were randomly divided into observation group and control group, 40 cases in each group. The patients in observation group and control group were treated with pantoprazole and omeprazole respectively. After 5 days of treatment, the clinical efficacy was observed. Results The effective rate of treatment in observation group was 95% and the incidence of adverse reactions was 7.5%, which was significantly better than 70% and 15.0% in control group. There was significant difference between two groups (P <0.05). The bleeding time in the observation group was (1.5 ± 0.5) d, which was significantly shorter than that in the control group (3.0 ± 0.5) d. The difference between the two groups was statistically significant (P <0.05). Conclusion Pantoprazole has obvious hemostasis in the treatment of upper gastrointestinal hemorrhage with few adverse reactions and significant clinical value.