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目的了解福建省闽清县孕龄期妇女麻疹、风疹和破伤风抗体水平,为预防控麻疹、风疹及新生儿破伤风提供依据。方法抽取2个镇19～30岁孕龄期妇女,采用酶联免疫吸附试验(ELISA)法定量检测血清麻疹、风疹和破伤风抗体水平。结果闽清县孕龄期妇女麻疹、风疹和破伤风抗体阳性率分别为88.8%、81.7%和100.0%,抗体几何平均浓度分别为782.77、46.40和0.046 6 U/ml。结论闽清县孕龄期妇女麻疹、风疹和破伤风抗体阳性率高,但还存在一定的阴性比例,且破伤风抗体几何平均浓度达不到足够的免疫保护,提示要建议孕龄期妇女孕前接种含麻疹、风疹的联合疫苗和破伤风类毒素疫苗。
Objective To understand the levels of measles, rubella and tetanus in pregnant women in pregnant and pastoral areas in Minqing County, Fujian Province, and to provide basis for the prevention of measles, rubella and neonatal tetanus. Methods Two pregnant women aged 19-30 years old were collected and serum antibody levels of measles, rubella and tetanus were quantitatively detected by enzyme-linked immunosorbent assay (ELISA). Results The positive rates of measles, rubella and tetanus antibodies in gestational age women in Minqing County were 88.8%, 81.7% and 100.0%, respectively. The geometric mean antibody concentrations were 782.77, 46.40 and 0.046 6 U / ml, respectively. Conclusions The positive rate of measles, rubella and tetanus antibodies in pregnant women of pregnant women of Minqing County is high, but there is still a certain negative proportion, and the geometric mean concentration of tetanus antibody can not reach enough immunoprotection, suggesting that women of gestational age should be advised before pregnancy Vaccination against measles, rubella and tetanus toxoid vaccines.