已知血液中的脂质是以脂蛋白的形式进行运转的。各种脂蛋白在动脉粥样硬化的发病中所起的作用不同。因而,测定它们的含量比单独测定血脂含量意义更加重大。虽然,超速离心是分离和定量脂蛋白的较好技术,但由于它设备昂贵、操作费时,故不能为一般实验室所采用。近年来发展起来的血清总低密度β脂蛋白含量的浊度测定法,被认为是予测高脂血症的简便有效的方法。可惜该项技术目前不论在方法学和临床应用方面均存在着许多问题。为此,我们首先制备纯的总低密度脂蛋白,解决了多年来未能 It is known that lipids in the blood are operated in the form of lipoproteins. Various lipoproteins play different roles in the pathogenesis of atherosclerosis. Therefore, the determination of their content is more important than the determination of lipid content alone. Although ultracentrifugation is a better technique for the separation and quantitation of lipoproteins, it can not be used by general laboratories due to its costly equipment and time-consuming operation. In recent years, the development of total serum low-density beta-lipoprotein content of the turbidimetric assay, is considered as a simple and effective method for the prediction of hyperlipidemia. Unfortunately, there are many problems with this technique both in terms of methodology and clinical application. For this reason, we first prepared pure total LDL, which solved the problem for many years