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目的研究高血压脑出血患者早期强化降压对血肿扩大的影响。方法比较案例分析法。选取我院2009年3月至2011年5月收治的高血压脑出血患者276例,根据降压情况分为常规组和早期强化组各138例,两组分别进行标准降压和强化降压,比较分析两组患者24 h后的血肿扩大情况。结果早期平均收缩压控制上,常规组和强化组分别为146 mm Hg、180 mm Hg,常规组降压效果显著优于常规组(P<0.05)。24 h后血肿扩大情况上,强化组血肿扩大10例,扩大率7.2%,常规组扩大24例,扩大率17.7%,强化组血肿扩大显著少于常规组(P<0.05)。结论高血压脑出血患者进行早期强化降压治疗能够有效控制血肿扩大情况,应当在临床上广泛应用。
Objective To study the effect of early step-down hypotension on the expansion of hematoma in patients with hypertensive intracerebral hemorrhage. Methods Compare case studies. 276 cases of hypertensive intracerebral hemorrhage admitted to our hospital from March 2009 to May 2011 were divided into the routine group and the early intensive group according to the hypotensive conditions, 138 cases each. The two groups were treated with standard antihypertensive and intensive antihypertensive, Comparative analysis of two groups of patients after 24 hours of hematoma enlargement. Results In the control of early mean systolic blood pressure, the routine group and the intensive group were 146 mm Hg and 180 mm Hg, respectively. The antihypertensive effect of the conventional group was significantly better than that of the conventional group (P <0.05). After 24 h, the hematoma enlarged in 10 cases, the expansion rate was 7.2% in the intensive group, 24 cases in the conventional group and 17.7% in the enlarged group. The expansion of the hematoma in the intensive group was significantly less than that in the conventional group (P <0.05). Conclusion Early hypertensive intracerebral hemorrhage in patients with intensive antihypertensive treatment can effectively control the expansion of hematoma, it should be widely used in clinical practice.