论文部分内容阅读
目的探讨肿瘤标志物和正电子发射断层/计算机断层扫描(PET/CT)在大肠癌术后随访中的作用及相互关系。方法43例大肠癌术后病人做全身PET/CT检查,并在一周内检测血癌胚抗原(CEA)、肿瘤抗原19-9(CA19-9)、肿瘤抗原50(CA50)水平,并与最终诊断进行比较,分析两种检查之间差异和相互关系。结果43例中,27例诊断大肠癌转移。肿瘤标志物诊断大肠癌术后转移的敏感性为59.3%,特异性为87.5%;PET/CT诊断大肠癌术后转移的敏感性为92.6%,特异性为93.8%。两者联合诊断的敏感性为100%,特异性为82.1%。结论PET/CT诊断大肠癌术后的转移敏感性和特异性较肿瘤标志物检测高,肿瘤标志物对PET/CT诊断具有补充作用,两者联合应用是诊断大肠癌术后转移的比较理想的方法。
Objective To investigate the role and correlation of tumor markers and positron emission tomography / computed tomography (PET / CT) in the follow-up of colorectal cancer patients. Methods Thirty-three patients with postoperative colorectal cancer underwent whole-body PET / CT examination. The levels of CEA, CA19-9 and CA50 were detected in one week, and were compared with the final diagnosis Compare and analyze the differences and correlations between the two tests. Results Of the 43 cases, 27 cases were diagnosed as metastatic colorectal cancer. The sensitivity and specificity of tumor markers for the diagnosis of colorectal cancer metastasis were 59.3% and 87.5% respectively. The sensitivity and specificity of PET / CT in the diagnosis of colorectal cancer metastasis were 92.6% and 93.8% respectively. The combined diagnosis of both the sensitivity was 100%, the specificity was 82.1%. Conclusion PET / CT has a higher sensitivity and specificity for detecting metastasis of colorectal cancer than tumor markers, and tumor markers can complement PET / CT diagnosis. The combined application of PET / CT and PET / CT is more ideal for the diagnosis of postoperative metastasis of colorectal cancer method.