Synthesis of Chitosan-Hydroxyapatite Composites and Its Effect on the Properties of Bioglass Bone Ce

来源 :Journal of Materials Science & Technology | 被引量 : 0次 | 上传用户:passkakaxi
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Chitosan-hydroxyapatite(CS-HA) composite powders were synthesized via in situ co-precipitation method,through the reaction of Ca(NO3)2 and H3PO4 in the simulated body fluid(SBF) containing appropriate amount of chitosan.The thermal evolution,microstructure and morphology were studied by TG-DTA(thermogravimetry-differential thermal analysis),XRD(X-ray diffraction),FTIR(Fourier transform infrared spectroscopy) and TEM(transmission electron microscopy).The in vitro bioactivity test showed that the obtained CS-HA composites had higher capability of inducing calcium ions deposition.Effects of CS-HA composites on the bioactivity and compressive strength of bioglass bone cement were investigated.The results indicated that the bioactivity of bioglass bone cement could be improved further when CS-HA composite powders were added into the cement,and appropriate amount of CS-HA additive was favorable for compressive strength improvement of bioglass bone cement. Chitosan-hydroxyapatite (CS-HA) composite powders were synthesized via in situ co-precipitation method, through the reaction of Ca (NO3) 2 and H3PO4 in the simulated body fluid (SBF) containing appropriate amount of chitosan.The thermal evolution, microstructure and morphology were studied by TG-DTA (thermogravimetry-differential thermal analysis), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy) and TEM (transmission electron microscopy). The in vitro bioactivity test showed that the obtained CS- HA composites had higher capability of inducing calcium ions deposition. Effects of CS-HA composites on the bioactivity and compressive strength of bioglass bone cement were investigated. The results indicated that the bioactivity of bioglass bone cement could be further further when CS-HA composite powders were added into the cement, and the appropriate amount of CS-HA additive was favorable for compressive strength improvement of bioglass bone cement.
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