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目的观察氯胺酮复合丙泊酚与伍用瑞芬太尼在小儿麻醉作用中的临床疗效。方法选取我院进行手术患儿136例,随机分为观察组和对照组各68例,对照组在手术中使用氯胺酮联合丙泊酚进行小儿静脉麻醉,观察组在手术中使用氯胺酮、丙泊酚伍用瑞芬太尼进行静脉麻醉,观察两组患儿麻醉前、术中以及术毕的麻醉效果,麻醉中血流动力学变化、氯胺酮使用量以及患儿苏醒时间,并进行比较。结果观察组麻醉效果明显优于对照组(P<0.01),平均动脉压(MAP)、心率(HR)在术中和术毕观察组明显低于对照组(P<0.05),在术前无明显差异(P>0.05),观察组术中氯胺酮使用量明显少于对照组(P<0.05),术毕苏醒时间也明显短于对照组(P<0.05)。结论氯胺酮复合丙泊酚伍用瑞芬太尼进行小儿静脉麻醉麻醉效果明显,氯胺酮使用量明显减少,术毕苏醒时间较短,值得在临床上推广使用。
Objective To observe the clinical efficacy of ketamine combined with propofol and remifentanil in pediatric anesthesia. Methods A total of 136 children undergoing surgery in our hospital were randomly divided into observation group (68 cases) and control group (68 cases). In the control group, ketamine combined with propofol was used to perform pediatric intravenous anesthesia during operation. Ketamine, propofol Wu remifentanil intravenous anesthesia was used to observe the anesthesia in anesthesia, intraoperative and postoperative anesthesia, hemodynamic changes in anesthesia, ketamine use and recovery time of children, and compared. Results The anesthesia in the observation group was significantly better than that in the control group (P <0.01). Mean arterial pressure (MAP) and heart rate (HR) in the observation group were significantly lower than those in the control group (P <0.05) (P 0. 05). The use of ketamine in the observation group was significantly less than that of the control group (P 0. 05), and the recovery time was also significantly shorter than that of the control group (P 0. 05). Conclusion Ketamine combined with propofol and remifentanil anesthesia in children with significant effect of anesthesia, ketamine significantly reduced the amount of use, recovery time is shorter, it is worth to promote the use of the clinic.