目的应用细胞遗传学方法研究染色体核型异常与生殖异常的关系。方法外周血及脐血淋巴细胞培养进行染色体G带分析。结果由于染色体核型异常的不同,出现不同的临床效应。结论在染色体异常核型中,均有不同程度的基因缺失,造成基因连锁的不平衡,因而出现一些临床效应。 Objective To study the relationship between chromosomal abnormalities and reproductive abnormalities by cytogenetics. Methods Chromosomal G-banding of peripheral blood and cord blood lymphocytes was performed. The results due to the different karyotype of chromosomal abnormalities, different clinical effects. Conclusions In karyotypes of chromosomal abnormalities, there are different degrees of gene deletion, resulting in the imbalance of linkage of genes and thus some clinical effects.