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经单克隆抗体间接免疫荧光术鉴定隐孢子虫卵囊(CSO)、确诊隐孢子虫肠炎34例,占同期腹泻小儿4.1％。年龄4月至7.6岁(2.5±1.7),典型大便为泡沫水便。6～9月份占74％。以苦参、黄芪为主中药治疗前、后同时测27名病人LBT和血清Ig水平并做PHA试验。除2例分别持续4～6月外,腹泻持续2～22d(10.9±7.1);CSO转阴为21.5±12.3d。PHA试验和LBT测试结果治疗前分别为7.9±2.4mm(直径),48.7％±10.1％,显著低于正常对照组,治疗后均恢复正常。作者推荐:对病因不明腹泻病人常规用番红-美兰和改良抗酸染色法查粪CSO;苦参、黄芪为主中药驱虫与增强细胞免疫力,有助康复;无症状排CSO可能是感染源。
Cryptosporidium oocysts (CSO) were identified by indirect immunofluorescence with monoclonal antibody. 34 cases of cryptosporidiosis were diagnosed, accounting for 4.1% of children with diarrhea in the same period. The age of April to 7.6 years (2.5 ± 1.7), the typical stool is foam water. June to September accounted for 74%. With Sophora, Astragalus-based Chinese medicine before and after treatment at the same time measuring 27 patients with serum LBT and Ig levels and PHA test. Diarrhea continued for 2 to 22 days (10.9 ± 7.1) except for 2 cases lasting from April to June. CSO negative conversion was 21.5 ± 12.3 days. The PHA and LBT test results were 7.9 ± 2.4mm (diameter) and 48.7% ± 10.1% before treatment, which were significantly lower than those of the normal control group and returned to normal after treatment. The authors recommend: diarrhea in patients with etiology of the conventional use of saffron - Meilan and improved acid-fast staining check stool CSO; Sophora, Astragalus-based traditional Chinese medicine de-worming and enhance cellular immunity, help recovery; asymptomatic row CSO may be Source of infection.