抗菌药物的联合运用在临床上较为常见。某些药物联合运用后具协同作用,而另一些则表现为拮抗作用。本文主要研究四环素类抗生素与抗虐疾药物联用后对20株临床分离到的大肠杆菌的体外抗菌活性的协同作用。试验材料:采用20株临床分离到的大肠杆菌作为试验菌株,所用的四环索类药物为去甲基金霉素盐酸盐、金霉素盐酸盐和土霉素盐酸盐;抗虐疾药物为奎宁二盐酸盐、氯奎二磷酸 The combined use of antibacterials is clinically common. Some drugs synergistically act synergistically, while others show antagonism. In this paper, the synergistic effect of tetracycline antibiotics and anti-malarial drugs on in vitro antibacterial activity of 20 clinically isolated E. coli strains was studied. Test Materials: Twenty strains of E. coli isolated clinically were used as test strains. The tetracyclic drugs used were norniclomycin hydrochloride, chlortetracycline hydrochloride and oxytetracycline hydrochloride. Anti-malarial The drug is quinine dihydrochloride, chloroquine diphosphate