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Ig 同种型的表达调节是一重要免疫基础理论课题。近年对Ig 同种型转换的调节机制有了进一步的认识。本文着重介绍T 细胞及其淋巴因子在Ig 同种型转换中的调节作用,同时也简介了抗原或丝裂原的作用以及B 细胞的自身调节功能。
Ig isoform expression regulation is an important immunological theory. In recent years, the regulation mechanism of Ig isotype conversion has been further recognized. This article highlights the regulatory role of T cells and their lymphokines in Ig isotype switching, as well as the role of antigen or mitogen and the self-regulatory role of B cells.