尸检证实黑色素性胆石在酒精性和非酒精性肝硬化患者发病率很高,约为非肝硬化患者的7倍。这种色素结石以胆红素钙盐或黑色素多聚体非结合胆红素(UCB)的形式存在。为了阐明肝硬化时胆结石的成因,本文对肝硬化、慢性活动性肝炎患者十二指肠液的胆汁中胆红素类型进行分析,并探索其与胆盐和磷脂的关系。 Autopsy confirmed melanin gallstone in alcoholic and non-alcoholic cirrhosis in patients with a high incidence, about 7 times the non-cirrhotic patients. This pigment stone with bilirubin calcium salt or melanin multimer non-conjugated bilirubin (UCB) form. In order to elucidate the causes of gallstone in cirrhosis, we analyzed the bilirubin type in duodenal fluid of patients with cirrhosis and chronic active hepatitis, and explored its relationship with bile salts and phospholipids.