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按间质性膀胱炎的定义来说,尿是无菌的,对尿或膀胱活检标本的详细检查去寻找细菌、病毒或真菌都投有找到。本病在任何年龄甚至儿童均可发病,但以30—50岁为最多见。因发病后要经多年才能诊断出来,因此显然地偏向较大年龄组。90％病例是女性病者,这是自身免疫病变的特点。组织学上的变化与结缔组织病变一致,这是为大家所熟知的。膀胱组织学标本上显示在粘膜和肌肉有不同程度的纤维化。水肿是很常见的。可观察到两种圆形细胞浸润形式,呈弥漫性及聚集在一起。严重病例虽然膀胱镜检查膀胱粘膜正常,但有广范围的上皮缺损区。浆细胞中等度增加及一些嗜酸细胞存在,通常是表明自身免疫疾病的特性。
According to the definition of interstitial cystitis, urine is sterile, a detailed examination of urine or bladder biopsy specimens to find bacteria, viruses or fungi are cast to find. The disease can occur at any age or even children, but the most common 30-50 years old. Because of the many years after the onset of the disease can be diagnosed, it is clearly biased towards the older age group. 90% of cases are female patients, which is characteristic of autoimmune lesions. Histological changes consistent with connective tissue disease, it is well known to everyone. Bladder histological specimens showed varying degrees of fibrosis in the mucosa and muscle. Edema is very common. Two types of round cell infiltrates were observed, diffuse and clustered together. Serious cases of cystoscopy bladder normal, but there is a wide range of epithelial defect area. Equal increase in plasma cells and the presence of some eosinophils are often signs of autoimmune disease.