本文利用动物犬建立了一种无损伤的估计心输出量的算法,对在正常换气和附加死区的30秒的部分再呼吸期间,应用CO_2的菲克方程的微分形式,利用菲克方程的微分形式无需对静脉PCO_2估计,也大大减少了心输出量对肺泡死区部分的敏感性,该过程是全自动化的,仅需极少照管,每3.5分钟提供一次心输出量的估计值,在16条狗的实验中得到心输出量的估计值同热稀释法比较时,得到斜率为 In this paper, a noninvasive estimation of cardiac output was established using animal models. During the 30-second partial re-breathing of normal ventilation and additional dead zones, the differential form of the Fick equation for CO 2 was used. The Fick equation Does not require a venous PCO 2 estimate and greatly reduces the sensitivity of cardiac output to the alveolar dead zone. This process is fully automated and requires minimal care, providing an estimate of cardiac output every 3.5 minutes, When the estimate of cardiac output obtained from experiments with 16 dogs was compared with the thermal dilution method, a slope of