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目的探讨单纯子宫腺肌病病灶切除术后联合促性腺激素释放激素激动剂治疗子宫腺肌病的疗效,并进行观察。方法对南阳市中心医院2011年2月至2012年2月收治的80例子宫腺肌病患者进行分组治疗。80例患者随机分为观察组与对照组,对照组患者在治疗子宫腺肌病时采取单纯子宫腺肌病灶切除手术;观察组患者采取病灶切除术联合促性腺激素释放激素激动剂治疗子宫腺肌病。对比两组治疗方式的临床疗效。结果术后对患者进行随访,平均随访2年。两组患者经治疗后痛经评分(VAS)及月经量与术前相比均有所好转。对照组患者月经量下降例数百分比为57.5%,观察组为87.5%,两组比较差异有统计学意义(P<0.05)。观察组患者术后痛经评分(1.01±1.24)分,明显低于对照组的(3.34±2.21)分,差异有统计学意义(P<0.05)。结论通过两组患者的对比治疗,病灶切除术联合促性腺激素释放激素激动剂治疗子宫腺肌病具有良好的临床效果,复发率低,值得在临床上推广应用。
Objective To investigate the curative effect of combined gonadotropin-releasing hormone agonist on adenomyosis after focal resection of adenomyosis and to observe. Methods Eighty patients with adenomyosis treated in Nanyang Central Hospital from February 2011 to February 2012 were divided into groups. 80 patients were randomly divided into observation group and control group, the control group of patients with adenomyosis in the treatment of adenomyosis resection alone; the observation group patients with focal resection combined with gonadotropin-releasing hormone agonist treatment of adenomyosis disease. Compare the clinical curative effect of two groups of treatment methods. Results The patients were followed up for 2 years on average. After treatment, dysmenorrhea score (VAS) and menstrual flow in both groups improved compared with that before operation. In the control group, the percentage of decline in menstruation was 57.5% in the observation group and 87.5% in the observation group, with significant difference between the two groups (P <0.05). The dysmenorrhea score (1.01 ± 1.24) in the observation group was significantly lower than that in the control group (3.34 ± 2.21), the difference was statistically significant (P <0.05). Conclusions The two groups of patients with comparative treatment, focal resection combined with gonadotropin-releasing hormone agonist in the treatment of adenomyosis has a good clinical effect, the recurrence rate is low, it is worth to promote the clinical application.