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本文旨在进一步评价硝酸盐对慢性心力衰竭患者的血液动力学效应,并与纯粹减低前负荷的止血带法以及同时扩张动脉与静脉血管的静脉滴注硝普钠法相比较,以探讨流出阻力减低与前负荷减低在硝酸盐血液动力学反应中的相对作用。方法:28例Ⅲ或Ⅳ级充血性心力衰竭的心肌病患者,用Swan-Ganz导管作右心插管和血液动力学检查。自肱动脉直接测量血压。用染料稀释法测定心排出量。以肺动脉楔嵌压或肺动脉舒张压作为左心室充盈
The purpose of this paper is to further evaluate the hemodynamic effects of nitrates in patients with chronic heart failure and to compare them with the tourniquet method of simply reducing the preload and the intravenous infusion of sodium nitroprusside, which simultaneously dilates arteries and veins, Relative to preload reduction in nitrate-hemodynamic responses. METHODS: Twenty-eight patients with grade III or IV cardiomyopathy with congestive heart failure were treated with Swan-Ganz catheterization for right heart cannulation and hemodynamic examinations. Blood pressure was measured directly from the brachial artery. Dye dilution method was used to determine cardiac output. Pulmonary arterial wedge pressure or pulmonary diastolic pressure as left ventricular filling