慢性阻塞性肺部疾病常易发生呼吸系感染.偶尔在适当抗生素治疗后,仍然不能使痰量减少和脓痰消除而需要住院治疗.假若患者病情持续不好转,而且伴有气急和喘息,应考虑有持续性呼吸系感染.患者常常要多次接受抗生素疗程,这可能扰乱鼻喉部的菌群,促进各种微生物或耐药致病菌的定居或侵入. Chronic obstructive pulmonary disease is often prone to respiratory infections, and occasionally after in the appropriate antibiotic therapy, still can not reduce the amount of sputum and purulent sputum eliminate the need for hospitalization .If the patient continues to be ill, and accompanied by shortness of breath and wheezing, should Considering a persistent respiratory infection, patients often have to undergo multiple antibiotic regimens, which can disrupt the nasal and laryngeal flora and promote the colonization or invasion of various microbes or resistant pathogens.