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目的:了解近年国内外抗结核药物的最新研究进展,并对其发展前景进行分析。方法:收集文献资料报道并结合临床情况进行分析。结果:目前国内外已研发了一批临床疗效较好的抗结核药物;严峻的结核病回升形势要求加速新型抗结核药物的研究开发。结论:缩短疗程,提高多耐药结核病(MDR-TB)疗效及对结核潜伏感染(LTBI)提供更有效的治疗是开发新抗结核药物要实现的目标。
Objective: To understand the latest research progress of anti-TB drugs at home and abroad in recent years, and to analyze its development prospects. Methods: Collecting the literature data and analyzing the clinical situation. Results: At present, a number of anti-TB drugs with good clinical efficacy have been developed at home and abroad. The severe TB recovery requires accelerating the research and development of new anti-TB drugs. CONCLUSION: The goal of developing new anti-TB drugs is to shorten the course of treatment, improve the efficacy of multi-drug resistant tuberculosis (MDR-TB) and provide more effective treatment of latent tuberculosis infection (LTBI).