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为探索将单纯疱疹病毒胸腺嘧啶核苷激酶基因／羟甲基无环鸟苷（ＨＳＶ１－ｔｋ／ＧＣＶ）药物敏感基因治疗系统应用于卵巢癌，本刊［１］已介绍体外实验结果，现将体内实验情况介绍如下。材料与方法１．细胞来源及培养详见文献［１］ ＧＣＶ仍由ＲｏｃｈＳｙｎｔｅｘ公司惠赠
To explore the application of herpes simplex virus thymidine kinase gene/hydroxymethyl acyclovir (HSV1-tk/GCV) drug sensitive gene therapy system to ovarian cancer, the results of in vitro experiments have been introduced in this issue [1]. The in vivo experiments are described below. Materials and Methods 1. Cell sources and culture are detailed in the literature [1] GCV is still a gift from RochSyntex