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目的分析缺血性脑血管患者颅外颈动脉粥样硬化斑块的发生率及斑块类型,以指导脑血管病的治疗和预防。方法选择入院的140例急性缺血性脑血管患者(包括脑梗死95例和短暂性脑缺血45例)为患病组,同期健康体检者50例为对照组,分别应用颈动脉彩超检测颅外颈动脉,检测其粥样硬化斑块发生率及斑块类型。结果患病组颅外颈动脉粥样硬化斑块的检出率80.7%与对照组48.0%比较,差异有显著性(P<0.01),脑梗死(CI)患者颅外颈动脉粥样硬化斑块的检出率82.1%和短暂性脑缺血(TIA)患者77.8%比较无显著性差异(P>0.05)。两组不稳定斑块的比例(39.7%和20.0%)比较有显著性差异(P<0.05)。结论颅外颈动脉粥样硬化斑块,尤其是不稳定斑块是缺血性脑血管病的病因之一。
Objective To analyze the incidence and types of extracranial carotid atherosclerosis plaque in patients with ischemic cerebrovascular disease to guide the treatment and prevention of cerebrovascular disease. Methods A total of 140 patients with acute ischemic cerebrovascular disease (including 95 cerebral infarction and 45 transient ischemic cerebral infarction) admitted to the hospital were selected as the control group. 50 healthy subjects were selected as the control group, External carotid artery to detect the incidence of atherosclerotic plaque and plaque type. Results The detection rate of extracranial carotid atherosclerosis was 80.7% in the diseased group compared with 48.0% in the control group (P <0.01). The extracranial carotid atherosclerosis plaque in the patients with cerebral infarction There was no significant difference in the detection rate of block between 82.1% and 77.8% of patients with TIA (P> 0.05). The two groups of unstable plaque (39.7% and 20.0%) were significantly different (P <0.05). Conclusion Extracranial carotid atherosclerotic plaque, especially unstable plaque, is one of the causes of ischemic cerebrovascular disease.