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肝硬化和慢性活动性肝炎患者常出现高免疫球蛋白血症。对其发生机制虽有一些研究,但尚未完全明了。本文通过慢性肝病患者末梢血中淋巴细胞体外培养,观察免疫球蛋白之合成,并与血中免疫球蛋白水平作比较,以探讨高免疫球蛋白血症的发生机制。材料和方法一、检查对象1982年英国皇家医师进修学院胃肠病科收治的慢性肝病22例,其中肝硬化14例,慢性活动性肝炎8例,皆有典型临床表现,并经活检确诊。此外,还有正常人22例作对照。
Patients with cirrhosis and chronic active hepatitis often have hypergammaglobulinemia. Although some studies on its mechanism have not yet been fully understood. In this paper, peripheral blood lymphocytes from patients with chronic liver disease were cultured in vitro to observe the synthesis of immunoglobulin, and compared with the level of blood immunoglobulin in order to explore the mechanism of hype immunoglobulinism. Materials and Methods First, the object of examination In 1982 the Royal College of Physicians, Department of Gastroenterology in the treatment of chronic liver disease in 22 cases, of which 14 cases of cirrhosis, chronic active hepatitis in 8 cases, all have a typical clinical manifestations, and confirmed by biopsy. In addition, there are 22 cases of normal controls.