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1995年S Takayama 等[1]发现一个可以显著促进Bcl-2抗凋亡作用的蛋白,将其命名为BAG-1(Bcl-2-associated athanogene 1)。BAG-1是一种可以定位于细胞浆和细胞核的多功能蛋白,它不仅可以作用于Bcl-2和
In 1995 S Takayama et al [1] found a protein that can significantly promote the anti-apoptotic effect of Bcl-2 and named it Bcl-2-associated athanogene 1. BAG-1 is a multifunctional protein that can be located in the cytoplasm and nucleus, it can not only act on Bcl-2 and