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患者,女,46岁,因失眠,多疑,无目的外走4年,加重半个月,疑其精神不正常而住院。体格检查未见异常,精神检查:存在评论性幻听,被害妄想、被跟踪感,注意力欠集中,情感淡漠,无自知力。诊断精神分裂症,给予口服氯氮平,每日3次,每次75mg;第3天出现困倦、胸闷,心率95次/分,未予处理;第4天仍表现困倦、走路不稳,定向力障碍,找不到厕所及自己床位,不知上、下午。查体可见四肢散在圆点状红疹,大小如小米粒,界限清晰微痒,未突出皮肤,压之能褪色。心电图示窦性心动过速,血压正
Patients, female, 46 years old, due to insomnia, suspicious, no purpose but to go four years, increased two weeks, suspected abnormal mental illness and hospitalization. No abnormal physical examination, mental examination: the existence of auditory hallucinations, murdered delusions, was tracking, attention deficit concentration, emotional apathy, ignorant. Diagnosed schizophrenia, given oral clozapine, 3 times a day, each 75mg; the first 3 days of sleepiness, chest tightness, heart rate 95 beats / min, untreated; the fourth day still showing sleepiness, walking instability, orientation Disability, can not find the toilet and their bed, I do not know, afternoon. Examination showed scattered limbs in the dot-like rash, the size of small grains, clear boundaries itching, did not highlight the skin, the pressure can fade. Electrocardiogram shows sinus tachycardia, positive blood pressure