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自身骨髓移植(ABMT)在临床上用于治疗某些血液系统的恶性肿瘤,但移植后复发率明显高于异基因骨髓移植,如何在ABMT前清除骨髓中残存的白血病细胞是解决这一问题的关键之一。人们已发展了物理学方法、化学方法、免疫学方法和生物学方法等多种净化技术,本文重点综述用联合法净化白血病细胞。
Autologous bone marrow transplantation (ABMT) is used clinically to treat certain hematologic malignancies, but the recurrence rate after transplantation is significantly higher than that of allogeneic bone marrow transplantation. How to clear residual leukemia cells in bone marrow before ABMT is a solution to this problem One of the keys. People have developed a variety of purification techniques such as physics methods, chemical methods, immunological methods and biological methods. This article focuses on synthesizing purging leukemia cells.