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目的:了解武汉大学中南医院临床标本中培养分离的铜绿假单胞菌(PAE)和鲍氏不动杆菌(ABA)的感染部位构成比及耐药性,为医师选择药物治疗细菌感染提供参考依据。方法:统计临床微生物室2015年第1季度感染标本中分离的PAE和ABA菌株数目及耐药情况,细菌分离与种型鉴定遵照卫计委组织制定的临床细菌学检验技术标准进行实验操作,药敏采用WHO认可的K-B法,实验室条件和实验全程严格实施室内质控。结果:2015年第1季度共培育出327株PAE和ABA;感染率最高的部位是下呼吸道,占53.2%,第2是泌尿道,占23.9%;对抗菌药物泛耐药的PAE和ABA阳性检出率分别达到10.5%和12.2%,耐亚胺培南PAE和ABA检出率分别达到31.0%和44.9%。结论:教学医院分离的PAE和ABA临床株的耐药率日益增长,医院应采取果断的干预手段,控制多药耐药菌引起的医院感染。
Objective: To understand the compositional ratio and drug resistance of infected parts of Pseudomonas aeruginosa (PAE) and Acinetobacter baumannii (ABA) isolated from clinical specimens of Zhongnan Hospital of Wuhan University, and provide a reference for physicians to choose drugs for the treatment of bacterial infections . Methods: The number of clinical isolates of PAE and ABA isolated from infected samples in the first quarter of 2015 and their drug resistance were analyzed. The bacterial isolation and type identification were carried out in accordance with the clinical bacteriological test standards developed by the SSC. The drugs Sensitive to adopt the KB method approved by the WHO, laboratory conditions and strict quality control throughout the laboratory. RESULTS: A total of 327 strains of PAE and ABA were bred in the first quarter of 2015. The highest infection rates were lower respiratory tract, accounting for 53.2%, and the second was urinary tract, accounting for 23.9%. PAE and ABA positive for pandemic antibiotics The detection rates of PAE and ABA in imipenem reached 31.0% and 44.9% respectively, reaching 10.5% and 12.2% respectively. Conclusion: The resistance rates of PAE and ABA clinical isolates isolated from teaching hospitals are increasing day by day. The hospital should take decisive intervention measures to control nosocomial infections caused by multidrug resistant bacteria.