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目的:探讨胸腔积液中的C反应蛋白(CRP)、腺苷脱氨酶(ADA)、乳酸脱氢酶(LDH)和总蛋白(TP)水平对胸腔积液鉴别诊断的价值。方法:检测95例不同病因引起胸腔积液的患者胸腔积液CRP、ADA、LDH和TP浓度。结果:结核组CRP和ADA平均含量为(27.14±21.72)U/L和(43.98±19.68)m g/L,显著高于癌症组和漏出液组(P<0.01);癌症组LDH平均含量为(859.90±551.69)U/L,显著高于结核组和漏出液组(P<0.01);漏出液组TP平均含量为(13.19±3.49)g/L,显著低于结核组和癌症组(P<0.01)。结论:检测胸腔积液中CRP、ADA、LDH和TP,有助于临床医生对胸腔积液性质的鉴别、形成的原因的诊断。
Objective: To investigate the differential diagnosis of pleural effusion in patients with pleural effusion, which includes C-reactive protein (CRP), adenosine deaminase (ADA), lactate dehydrogenase (LDH) and total protein (TP) Methods: The concentrations of CRP, ADA, LDH and TP in pleural effusion were detected in 95 patients with pleural effusion of different etiology. Results: The mean levels of CRP and ADA in tuberculosis group were (27.14 ± 21.72) U / L and (43.98 ± 19.68) mg / L respectively, which were significantly higher than those in cancer group and leaking fluid group (P <0.01) 859.90 ± 551.69) U / L, which was significantly higher than that of tuberculosis group and leakage group (P <0.01). The average content of TP in the leakage group was (13.19 ± 3.49) g / L, which was significantly lower than that in the tuberculosis group and the cancer group (P < 0.01). Conclusion: The detection of CRP, ADA, LDH and TP in pleural effusions is helpful for clinicians to identify the cause of pleural effusion.