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本文报导741例上海市结核病初治患者不同年份的耐药性测定,耐药率1964～66年为19.2%,1978～84三个年份组分别为26.1%、23.7%、22.6%,虽有升降,但经统计学处理(P>0.05)无显著性差异。并对522例1980～84年各年龄组的耐药率进行观察,随着年龄的增长,耐药率均有不同下降,15～29岁组与45岁以上的二组比较,经统计学处理(P<0.05)有显著性差异。二线药物的耐药率近几年来仍维持在较低水平;RFP 为1.4%,EB 为0.5%、KM 与 TH1321均为0.8%。
This article reports 741 cases of tuberculosis in Shanghai in different years of initial drug resistance measured in 1964 to 66 years was 19.2%, 1978 ~ 84 three years were 26.1%, 23.7%, 22.6%, although the lift , But no statistically significant difference (P> 0.05). The resistance rates of 522 age groups from 1980 to 84 were observed. With the increase of age, the drug resistance rates decreased. The difference between the age groups of 15 ~ 29 and the age group of 45 years old was statistically significant (P <0.05) there is a significant difference. Second-line drug resistance rates remained low in recent years; RFP was 1.4%, EB was 0.5%, and both KM and TH1321 were 0.8%.