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自1955年Frank首先用甲苯磺丁脲(Tolbutamide)治疗糖尿病以来,已有30多年。随着糖尿病患病率的增加,口服降血糖药已在全世界广泛地应用。全世界有70～80%的糖尿病患者用口服降血糖药治疗。但在1971年美国大学糖尿病研究小组(U
More than 30 years have passed since Frank first treated diabetes with Tolbutamide in 1955. Oral hypoglycemic agents have been widely used throughout the world as the prevalence of diabetes increases. 70-80% of diabetic patients in the world are treated with oral hypoglycemic agents. But in 1971 the American University Diabetes Research Group (U.