论文部分内容阅读
作者等对用常规量氮基甙类抗生素的患者,反复测定血镁浓度,发现常可引起低镁血症。 氨基甙类抗生素常规量(3～5mg/Kg)治疗55人,其中38人用妥布霉素、15人用庆大霉素、2人用丁胺卡那霉素。将血镁浓度低于1.6mg/dl者定为低镁血症则21人发生低镁血症(占88％,其中妥布霉素15人、庆大霉素5人、丁胺卡那霉素1人),其中13人为中度降低(血镁少于1.4mg/dl),5人为严重降低(血镁少于1.0mg/dl)。在镁摄取量不足或使用不含镁的液体时。低镁血症发生率高,在低镁血症与正常血镁患者之间,所用的氨基甙类抗生素的剂量与时间无差别。从开始用药至发生低镁血症的平均时间为8.6±0.6日,5人(24％)平均在2.3±0.3日发生低镁血症,均呈重度。所有
The authors with conventional doses of nitrogen-based glycosides in patients with repeated measurements of blood magnesium concentration, often found can cause hypomagnesemia. Aminoglycoside conventional amount (3 ~ 5mg / Kg) treatment of 55 people, of whom 38 were tobramycin, 15 for gentamicin, 2 for amikacin. The blood magnesium concentration of less than 1.6mg / dl were identified as hypomagnesemia in 21 patients with hypomagnesemia (88%, of which tobramycin 15, gentamicin 5, kanamycin 1), of whom 13 were moderately reduced (serum magnesium less than 1.4 mg / dl) and 5 were severely reduced (serum magnesium less than 1.0 mg / dl). When magnesium intake is inadequate or magnesium-free liquid is used. Low incidence of hypomagnesemia, hypomagnesemia and normal blood magnesium patients, the dose of aminoglycoside antibiotics and no difference in time. From the beginning of medication until the average time for hypomagnesemia was 8.6 ± 0.6 days, 5 (24%) had hypomagnesemia on average of 2.3 ± 0.3 days and showed severe hypomagnesemia. all