论文部分内容阅读
目的观察吸入噻托溴铵粉治疗稳定期COPD患者的综合疗效和不良反应。方法稳定期中度以上COPD患者吸入噻托溴铵粉治疗,比较吸入前后每天使用缓解药物次数、呼吸困难评分、肺功能指标和6min步行距离(6MWT)改善情况。结果治疗后使用缓解药物次数减少,呼吸困难评分下降、肺功能指标(FEV1,FVC和FEV1%)和6MWT均有所改善,药物不良反应少见且轻微。结论中度以上COPD患者吸入噻托溴铵粉疗效肯定且安全。
Objective To observe the combined effects and adverse reactions of inhaled tiotropium bromide in patients with stable COPD. Methods Patients with COPD at stable stage were treated with tiotropium bromide inhalation. The number of relief medication, dyspnea score, pulmonary function index and 6MWT distance before and after inhalation were compared before and after inhalation. Results After treatment, the number of relieving drugs decreased, dyspnea score decreased, lung function indexes (FEV1, FVC and FEV1%) and 6MWT were improved. Adverse drug reactions were rare and slight. Conclusion In patients with moderate or severe inhaled tiotropium bromide positive and safe.