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胃肠道原发性恶性淋巴瘤(Primary Mallgnant Lymphoma of the Gas—tronitestinal Tract简称PMLGL)为一种临床上少见的原发于胃肠壁内淋巴滤泡的恶性肿瘤。我院自1975—1991年共收治胃肠道恶性肿瘤3242例,其中PMLGL为58例,占胃肠道恶性肿瘤的2.8％。诊断:采用Dawson标准,病理组织学分型:基本上按国际标准分类。病期按照修正的Ann Arbor分期标准划分。因本病没有特异的临床症状和体症,早期诊断困难,近年来,B超引导下针吸活检及纤维内窥镜的应用对此病的早期诊断有帮助。关于胃肠道恶性淋巴瘤的治疗,多数肿瘤学家主张首选手术切除,采用有计划的手术、放疗、化疗、免疫等综合治疗。在影响此病预后的诸多因素中临床病理分期是最重要的因素。
Primary Malignant Lymphoma of the Gastrointestinal Tract (PMLGL) is a clinically rare malignant lymphoid follicle originating in the gastrointestinal wall. In our hospital from 1975 to 1991, there were 3242 cases of gastrointestinal cancers, of which 58 cases were PMLGL, accounting for 2.8% of the gastrointestinal cancer. Diagnosis: Dawson criteria, histopathological typing: basically classified according to international standards. The disease period was divided according to the revised Ann Arbor staging criteria. Due to the absence of specific clinical symptoms and signs of the disease, early diagnosis is difficult. In recent years, B-ultrasound-guided needle biopsy and the use of fiber endoscopy have helped in the early diagnosis of this disease. With regard to the treatment of gastrointestinal lymphoma, most oncologists advocate the preferred surgical resection, and use a combination of planned surgery, radiotherapy, chemotherapy, and immunization. The clinical pathological staging is the most important factor in many factors affecting the prognosis of the disease.