帕金森病(PD)老年者常有体重减轻,目前对其原因了解甚少,本研究对一组体重减轻的PD患者,确定是否存在营养不良并判断可能的病因。方法 15名PD患者,平均年龄73.9岁(68.3～80.5),12个月前至少体重减轻5kg;对照组为随机选择的15名健康老年人,年龄和性别与患者组相匹配。PD患者至少表现震颤、强直、运动迟缓其中的两项症状,服用左旋多巴反应良好,研究前病情至 Parkinson’s disease (PD) The elderly often have weight loss, and at present little is known about the cause. This study examined whether a group of PD patients with weight loss had malnutrition and judged possible causes. Methods Fifteen patients with PD had an average age of 73.9 years (68.3-80.5), with a weight loss of at least 5 kg 12 months earlier. The control group consisted of 15 healthy elderly patients randomly selected and matched for age and gender. PD patients showed at least tremor, ankylosis, bradykinesia, two of the symptoms, taking good response to levodopa, the study before the disease to