目的　为掌握天台县肾综合征出血热 (HFRS)流行规律与疫源地类型。方法　采用间接免疫荧光法 (IFAT)检测EHF病人血清中抗体 ,采用直接免疫荧光法 (FAT)检测鼠肺汉坦病毒 (HV)抗原。结果　 1984～ 2 0 0 0年天台县共发病 5 62 0例 ,486例HFRS恢复期病人血清学分型结果为 ,Ⅰ型 (汉滩型 )占60 91% ,Ⅱ型 (汉城型 )占 3 2 5 1% ,未定型占 6 5 8%。夏季和冬春季有二个发病高峰 ,青壮年农民发病最多。检测小兽汉坦病毒 (HV)抗原 2 0 0 97只 ,阳性 871只 ,带病毒率为 4 0 6%。结论　天台县是以Ⅰ型 (汉滩型 )为主的混合型HFRS疫区 Objective To understand the prevalence and type of HFRS in Tiantai County. Methods Antibody was detected by indirect immunofluorescence (IFAT) in serum of EHF patients. Hantavirus (HV) antigen was detected by direct immunofluorescence assay (FAT). Results A total of 5620 cases were found in Tiantai County from 1984 to 2000. Serological typing results of 486 HFRS convalescent patients were 60 91% of type I (Han dynasty), 32 (type Ⅱ) 5 1%, unconfigured 65.8%. There are two peak incidences in summer and winter and spring, with the most incidence among young and middle-aged peasants. A total of 2 0 97 rabies virus Hantavirus (HV) antigens were detected, with a positive rate of 871 and a virus prevalence of 406%. Conclusion Tiantai is a type I (Hantan type) predominant mixed HFRS epidemic area