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流行病学研究提示了使用高剂量复合口服避孕药(OC)和严重心血管并发症,如心肌梗塞、卒中和静脉血栓栓塞之间的关系。减少每日乙炔雌二醇(EE)的剂量至30μg,心血管并发症明显减少。含有炔诺酮的复合OC中,EE进一步减少到每片含30μg以下,导致了高的妊娠率,并且由于这些孕激素的
Epidemiological studies suggest a relationship between the use of high-dose combination oral contraceptives (OC) and severe cardiovascular complications such as myocardial infarction, stroke and venous thromboembolism. Reduce the daily dose of ethinyl estradiol (EE) to 30μg, a significant reduction in cardiovascular complications. In norethindrone-containing complex OCs, EE is further reduced to below 30 μg per tablet, resulting in high pregnancy rates, and since these progestin