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目的掌握无锡市流行性感冒(流感)流行规律和优势毒株的变化规律,为流感防控提供依据。方法收集无锡市2011—2013年2家哨点医院的流感样病例(ILI)数据,采用实时荧光聚合酶链式反应(PCR)对每周采集的ILI进行流感病毒核酸检测,对所得数据进行统计分析。结果 2011—2013年间,无锡市ILI%为1.64%,年龄构成以0~5岁为主(68.98%)。病原学数据显示,3年平均阳性率为11.17%,其中B型占35.88%,甲型H1N1型占15.51%,季节性H3N2型占48.61%,未发现季节性H1N1阳性病例。各年龄组人群感染流感毒株型别不同(χ2=27.799,P<0.01)。结论 2011—2013年无锡市流感流行强度处于正常水平;季节性H3N2和B型交替成为2011年4月后的优势毒株。应加强流感的预防和控制,特别是对流感检出较高的年龄组应更加关注。
Objective To understand the epidemiology of influenza (influenza) and the variation of dominant strains in Wuxi, and to provide basis for prevention and control of influenza. Methods Influenza-like illness (ILI) data from two sentinel hospitals in Wuxi from 2011 to 2013 were collected. Fluorescent nucleic acid was detected by real-time fluorescence polymerase chain reaction (PCR) on ILI collected weekly, and the data were statistically analyzed analysis. Results During 2011-2013, the ILI% in Wuxi was 1.64%, with the age of 0-5 years (68.98%). According to the etiological data, the average positive rate in 3 years was 11.17%, of which 35.88% were type B, 15.51% were type A H1N1 and 48.61% were seasonal H3N2, and no case of seasonal H1N1 was found. Influenza strains in different age groups were different (χ2 = 27.799, P <0.01). Conclusion The epidemic intensity of influenza in Wuxi was normal at 2011-2013. Seasonal H3N2 and B were alternately the dominant strains after April 2011. Greater attention should be paid to the prevention and control of influenza, especially in the higher age group of influenza.