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目的回顾性分析糖尿病并发周围神经病变情况和相关因素。方法收集106例糖尿病患者,进行分组,1组(对照组):75例,均未发生肌电图改变及PN;两组:31例,只发生肌电图改变;3组:5例,DM确诊时已经出现PN;4组:21例,DM确诊后出现肌电图改变及(或)PN,分别从发病年龄、平均病程、确诊时FPG、出现PN时FPG等相关因素进行比较。结果在106例临床确诊的DM患者中,发现24.6%并发PN,其中2型DM并发率26.2%。DM确诊时已有4.7%出现PN,均为2型DM;DM确诊后PN发生率19.8%,2型并发率20.2%,1型并发率18.2%,单纯肌电图改变为4.7%。DM并发PN在发病年龄、平均病程及发病时PGF与对照组比差异有显著性(P<0.01),并发PN时FPG与DM确诊时FPG比差异有显著性(P<0.001),均呈正相关。结论糖尿病(DM)是一组常见的内分泌代谢疾病,常并发神经病变,特别是周围神经病变(PN)。它的发生、发展与DM的发病年龄、病程长短、血糖水平有关。1型糖尿病早期多不伴有神经并发症,2型糖尿病在就诊时,就已经存在神经病变,我们应该重视。
Objective To retrospectively analyze the incidence of peripheral neuropathy in diabetic patients and related factors. Methods A total of 106 patients with diabetes mellitus were enrolled in this study. One group (control group): 75 cases without any change of electromyogram and PN; two groups: 31 cases with only EMG changes; 3 cases: 5 cases with DM There were PN in the diagnosis; 4 cases: 21 cases. The changes of EMG and / or PN appeared after DM was diagnosed. The related factors such as age of onset, average duration of disease, FPG at diagnosis, and FPG at PN were compared. Results In 106 cases of clinically diagnosed DM patients, 24.6% were found to be complicated by PN, of which type 2 DM complicated with 26.2%. PN was diagnosed in 4.7% of DM patients at the time of diagnosis. Both of them were type 2 DM. The incidence of PN was 19.8%, 20.2%, 18.2% and 4.7% respectively. There were significant differences in PGF between the two groups (P <0.01). There was a significant difference (P <0.001) between FPG and DM in the diagnosis of PN complicated with PN . Conclusion Diabetes mellitus (DM) is a group of common endocrine and metabolic diseases, often complicated by neuropathy, especially peripheral neuropathy (PN). Its occurrence, development and age of onset of DM, duration of disease, blood glucose levels. Early type 1 diabetes are not associated with neurological complications, type 2 diabetes at the time of treatment, there have been neuropathy, we should pay attention.