长期以来,已知丙烯腈有高度的急性毒性。1977年发表了一篇接触丙烯腈的工人的流行病学调查和对大鼠进行的长期研究结果,对丙烯腈的致癌性提出了相当大的怀疑。一些研究也证实丙烯腈对各种不同的动物种属有致畸作用和胚胎毒性作用。尽管丙 Acrylonitrile has long been known to be highly acutely toxic. An epidemiological survey of workers exposed to acrylonitrile and a long-term study in rats published in 1977 raised considerable doubt about the carcinogenicity of acrylonitrile. Some studies have also confirmed that acrylonitrile has teratogenic and embryotoxic effects on a variety of animal species. Although C