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肠道非特异性炎症性疾病即溃疡性结肠炎和克隆氏病的治疗分为保守疗法和外科疗法二种,应根据不同病例选择最佳治疗方案。横滨市立大学第二外科在过去十几年内,共收治溃疡性结肠炎254例(其中手术40例),Crohn 氏病40例(其中手术31例),治疗体会如下。药物疗法主要用磺胺和肾上腺皮质激素药物,有一定疗效。但在无效或出现副作用情况下可改用其他药物。如出现磺胺药副作用时可改用某些水杨酸化合物类药物;肾上腺皮质激素无效时改用6-巯基嘌呤或环孢子菌素等药物可能奏效。近年营养疗法的进步对肠道炎症性疾病的治疗起到很大作用。对改善上述两疾病的重症病人全身状态,稳定局部病变,减少手术危险性方面疗效显著,成为不可缺少的治疗手段。对Crohn 氏病,能促进其病灶愈合,是该病的主要疗法。但对已显著纤维化致肠管狭窄和形成瘘管的克隆病患者疗效欠佳,因而选择适宜的手术时机重新成为课题。长期的饮食调整尤为重要。这类病人常在本病症
Intestinal non-specific inflammatory diseases that ulcerative colitis and Crohn’s disease treatment is divided into two kinds of conservative treatment and surgical treatment, should be based on different cases to choose the best treatment. Yokohama City University, the second surgical department in the past ten years, received a total of 254 cases of ulcerative colitis (40 cases of surgery), 40 cases of Crohn’s disease (including 31 cases of surgery), the treatment is as follows. Drug therapy with sulfa and adrenal hormones drugs, have a certain effect. However, in the event of ineffective or side effects may switch to other drugs. Sulfa drug side effects such as the use of certain salicylic acid compounds may be switched to drugs; cortisone ineffective use of 6-mercaptopurine or cyclosporin and other drugs may work. In recent years, advances in nutrition therapy have played a significant role in the treatment of intestinal inflammatory diseases. To improve the above two diseases in patients with severe systemic disease, stable local disease, reduce the risk of surgery significant effect has become an indispensable treatment. Crohn’s disease, can promote the healing of its lesions, is the main therapy. However, the fibrosis of fibrosis caused by bowel stenosis and the formation of fistula colon disease ineffective, so choose the appropriate timing of surgery to become a topic again. Long-term dietary adjustments are particularly important. Such patients often in this condition