人偏肺病毒(Human metapneumovirus,h MPV)和它相近的同病毒科成员呼吸道合胞病毒一样,是儿童下呼吸道感染的主要病因。h MPV也是世界范围内引起免疫功能低下者和老年人发病及死亡的常见原因。感染的反复发生也加重了医疗负担。然而,目前并没有针对h MPV的特异性预防措施。本文着重概述目前关于阐述h MPV疫苗的研究进展的文献。我们认为对宿主应答中病毒蛋白的作用更好的 Human metapneumovirus (hMPV), like its counterpart of the virus family, respiratory syncytial virus, is the major cause of lower respiratory tract infection in children. h MPV is also a common cause of morbidity and mortality in immunocompromised and elderly individuals worldwide. The recurrence of infections also aggravates the medical burden. However, no specific precautions against hMPV are currently available. This article highlights the current literature on the development of hMPV vaccines. We think the effect on viral proteins in host response is better