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目的：调查新生五项乙型肝炎病毒标志物（ＨＢＶＭ）及肝功能的结果，达到控制乙肝传染的目的。方法：选用四届入学新生１４６２份血清，采用酶联免疫吸咐法（ＥＬＩＳＡ）检测五项ＨＢＶＭ，应用改良赖氏法，检测了肝功能。结果：ＨＢＶＭ阳性组合例数７０９例，占４８．５０％，乙肝病毒抗原（ＨＢｓＡｇ）阳性者１４９例，占１０．８８％。乙肝病毒抗体（ＨＢｓＡｂ）阳性占３０２例，占２０．６６％。丙氨酸转氨酶（ＧＰＴ）异常者５３例，占３．６３％。结论：新生乙型肝炎病毒（ＨＢＶ）感染人数及ＨｓＡｇ携带者较多，对结果异常者应采取积极治疗和适当管理。ＨＢｓＡｂ阳性率逐年增高，结果提示，注射乙肝疫苗是防止乙肝传染的重要措施。
OBJECTIVE: To investigate the results of five newborn hepatitis B virus markers (HBVM) and liver function in order to control the hepatitis B infection. Methods: A total of 1462 serums from four freshmen were enrolled in this study. Five HBVMs were detected by enzyme-linked immunosorbent assay (ELISA), and liver function was tested by modified Lai’s method. Results: There were 709 HBVM positive cases (48.50%) and 149 positive HBsAg positive cases (10.88%). Hepatitis B virus antibody (HBsAb) positive accounted for 302 cases, accounting for 20.66%. 53 cases of abnormal alanine aminotransferase (GPT), accounting for 3.63%. Conclusion: The number of newly diagnosed hepatitis B virus (HBV) infection and HsAg carriers are more, and those with abnormal results should take active treatment and appropriate management. HBsAb positive rate increased year by year, the results suggest that injection of hepatitis B vaccine is an important measure to prevent hepatitis B infection.