【摘 要】
：
AIM: To explore whether polymorphisms of the CYPIA1 and GSTM1 genes are associated with susceptibility of stomach cancer.METHODS: A total of 102 stomach cancer
【机 构】
：
the Center of Tumour Treatment,the Institute of Basic Medicine
论文部分内容阅读
AIM: To explore whether polymorphisms of the CYPIA1 and GSTM1 genes are associated with susceptibility of stomach cancer.METHODS: A total of 102 stomach cancer cases and 62 healthy persons were diagnosed by pathology in 1998-2000 in the Qilu Hospital of Shandong University. Gene polymorphisms were detected by the PCR using sequence-specific primers. Data analysis of the case-control study was carried out using the unconditional logistic method.RESULTS: After adjustment for age, sex, educational levels, and occupation, the risk factors for stomach cancer were shown to be smoking, Helicobacter pylori(H pylori),and presence of the CYPIM G/G and GSTM1 O/O genotypes.Interaction was observed between the combined genotypes of either CYPIA1 G/G and GSTM1 O/O or H pylori infection,or GSTM1 O/O and H pylori infection or smoking.CONCLUSION: Polymorphisms of the CYPIA1 and GSTM1 genes, H pylori infection and smoking are related to susceptibility to stomach cancer.
其他文献
A novel 2D cellular automata (CA) model has been developed for description of normal grain coarsening and abnormal grain coarsening process. The program reflect
Spraying a 1-2 mmol/L solution of NaHSO3 on the leaves of wild-type rice (Oryza sativa L.)Kitaake (WT), phosphoenolpyruvate carboxylase (PEPC) transgenic (PC) r
The nitrogen transformation in maize soil after application of different organic manure was studied. The nitrogen mineralization in surface soil, NO3--N dynamic
The effects of NaCl stress on the H+ -ATPase, H+ -PPase activity and lipid composition of plasma membrane(PM) and tonoplast(TP) vesicles isolated from roots and
Electron beam was successfully used for the degradation of 2-chlorophenol (2-CP) and 4-chlorophenol (4-CP) in aqueous solutions in this research. The effect of
Fertilizers contribute greatly to high yields but also result in environmental non-point contamination, including the emission of greenhouse gas(N2O) and eutrop
Species abundance and seasonal succession of copepods in aline-alkaline ponds were studied in Zhaodian Fish Farm, Gaoqing County, Shandong Province, from 5 Apri
While non-point pollution from agriculture has become an increasingly serious problem in China, some progress has been made in studying the causal biophysical p
Imposex,specifically caused by TBT pollution,refers to the superimposition of male sexual characteristics in gastropod females.Seasonal variation of imposex int
The Beijing 325-m Meteorological Tower (325MT) is used to observe the vertical variation of solar radiation. Results of the experiments indicate that the automa