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60例恶性胸腔积液患者胸腔留置导管行胸腔闭式引流,尽量引流完积液后再注入药物;治疗组应用DDP60mg联合鸦胆子油乳40ml及DXM5mg注入胸腔,对照组单用DDP60mg及DXM5mg注入胸腔,每周1次,连续2次。治疗组有效率为83.3%,对照组有效率为46.7%(χ2=8.87,P<0.05);KPS生活质量改善方面,治疗组有效率为86.7%,对照组有效率为53.3%(χ2=8.23,P<0.05);两组毒副反应无显著性差异。
60 cases of malignant pleural effusion in patients with thoracic catheter indwelling thoracic drainage, as far as possible drainage of fluid after injection of drugs; the treatment group with DDP60mg combined Brucea javanica oil emulsion 40ml and DXM5mg into the chest, the control group with DDP60mg and DXM5mg into the chest , Once a week, 2 times in a row. In the treatment group, the effective rate was 83.3% in the control group and 46.7% in the control group (χ2 = 8.87, P <0.05). The improvement of KPS was 86.7% in the treatment group and 53.3% in the control group (χ2 = 8.23 , P <0.05). There was no significant difference between the two groups in side effects.