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目的探讨血糖控制对社区原发性高血压合并2型糖尿病患者血压控制及内皮功能的影响。方法选择东莞市沙田镇社区86例原发性高血压合并2型糖尿病患者,所有患者均给予降压、降糖治疗,治疗8周后根据血糖控制情况分成观察组45例(空腹血糖<7.0 mmol/L)和对照组41例(空腹血糖≥7.0 mmol/L),比较两组患者的血压水平及内皮功能。结果观察组收缩压、舒张压明显低于对照组(P<0.05);血浆内皮素及尿清蛋白排泄率降低程度均明显低于对照组(P<0.05)。结论血糖控制有助于控制高血压合并2型糖尿病患者血压水平,改善血管内皮功能,提高治疗效果。
Objective To investigate the effects of glycemic control on blood pressure control and endothelial function in patients with type 2 diabetes mellitus and essential hypertension in community. Methods Eighty-six patients with essential hypertension and type 2 diabetes mellitus were selected in Shatian community. All patients were given antihypertensive treatment and hypoglycemic treatment. After 8 weeks of treatment, the patients were divided into observation group (fasting blood glucose <7.0 mmol / / L) and control group (fasting blood glucose> 7.0 mmol / L). The blood pressure and endothelial function were compared between the two groups. Results The systolic pressure and diastolic pressure of the observation group were significantly lower than those of the control group (P <0.05). The levels of plasma endothelin and urinary albumin excretion were significantly lower than those of the control group (P <0.05). Conclusion The blood sugar control helps to control the blood pressure of patients with type 2 diabetes mellitus and improve the endothelial function and improve the therapeutic effect.